Negri Bruno, Calvo-Guirado José Luis, Maté Sánchez de Val José Eduardo, Delgado Ruiz Rafael Arcesio, Ramírez Fernández María Piedad, Gómez Moreno Gerardo, Aguilar Salvatierra Antonio, Guardia Javier, Muñoz Guzón Fernando
Collaborator professor of Master in Implant Dentistry, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain; senior lecturer in General and Implant Dentistry, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain; associate professor in Restorative Dentistry, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain; senior lecturer of Farmacological Interactions, Faculty of Dentristry, University of Granada, Granada, Spain; lecturer in General Veterinary, Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
Clin Implant Dent Relat Res. 2013 Dec;15(6):799-808. doi: 10.1111/j.1708-8208.2011.00431.x. Epub 2012 Jan 11.
The aim of this study was to evaluate the early bone response of tapered and cylindrical root form implants with two different surface treatments in fresh extraction sockets after 4 and 8 weeks.
Surface treatments and implant design comprised (n = 9 each): tapered with dual acid-etched surface; tapered with dual acid-etched and sandblasted surface (T DAE SB); cylindrical with dual acid-etched surface (C DAE); and cylindrical with dual acid-etched and sandblasted surface (C DAE SB). Implants were placed in the distal sockets of mandibular premolars (2 P2, 3 P3, 4 P4 ) of six beagle dogs, remaining in vivo for 4 and 8 weeks. After sacrifice, the implants were subjected to torque to the point of interface fracture and subsequently nondecalcified for histomorphological study. Statistical analysis was performed by a General Linear Model (GLM) analysis of variance model with a significance level of 5%.
Torque to interface fracture was significantly greater for the C DAE SB group than for the other groups (p < .001). Histomorphological analysis showed woven bone formation around all implant surfaces at 4 weeks and its replacement by lamellar bone at 8 weeks. Study time (4 or 8 weeks) did not affect torque measures.
The double acid-etched and sandblasted sample surface increased early bone biomechanical fixation of both cylindrical and tapered root form implants. The cylindrical root form implants showed higher torque to interface fracture values when compared with the tapered root form implants. The C DAE SB surface group showed the highest biomechanical fixation values (p < .001).
本研究旨在评估在新鲜拔牙窝中植入的具有两种不同表面处理的锥形和圆柱形牙根形态种植体在4周和8周后的早期骨反应。
表面处理和种植体设计包括（每组n = 9）：双酸蚀表面的锥形种植体；双酸蚀和喷砂表面的锥形种植体（T DAE SB）；双酸蚀表面的圆柱形种植体（C DAE）；双酸蚀和喷砂表面的圆柱形种植体（C DAE SB）。将种植体植入6只比格犬下颌前磨牙（2 P2、3 P3、4 P4）的远中牙槽窝，在体内留存4周和8周。处死动物后，对种植体施加扭矩直至界面断裂，随后进行非脱钙处理以进行组织形态学研究。采用一般线性模型（GLM）方差分析模型进行统计分析，显著性水平为5%。
C DAE SB组至界面断裂的扭矩显著高于其他组（p <.001）。组织形态学分析显示，4周时所有种植体表面周围均有编织骨形成，8周时被板层骨替代。研究时间（4周或8周）不影响扭矩测量结果。
双酸蚀和喷砂的样本表面增加了圆柱形和锥形牙根形态种植体的早期骨生物力学固定。与锥形牙根形态种植体相比，圆柱形牙根形态种植体至界面断裂的扭矩值更高。C DAE SB表面组显示出最高的生物力学固定值（p <.001）。
