挪威接种疫苗后19A型肺炎球菌疾病的增加是由ST199复合体中对青霉素敏感菌株的扩增所驱动的。
Postvaccination increase in serotype 19A pneumococcal disease in Norway is driven by expansion of penicillin-susceptible strains of the ST199 complex.
作者信息
Vestrheim Didrik F, Steinbakk Martin, Aaberge Ingeborg S, Caugant Dominique A
机构信息
Department of Bacteriology and Immunology, Norwegian Institute of Public Health, Oslo, Norway.
出版信息
Clin Vaccine Immunol. 2012 Mar;19(3):443-5. doi: 10.1128/CVI.05563-11. Epub 2012 Jan 11.
Abstract
Serotype replacement in invasive pneumococcal disease has been observed after widespread use of the 7-valent pneumococcal conjugate vaccine (PCV7). Replacement is dominated by penicillin-nonsusceptible serotype 19A in several countries. Antibiotic selection pressure has been proposed to interact with immunization, leading to rapid replacement. In Norway, where prescription of antibiotics is limited, post-PCV7 replacement by serotype 19A is dominated by penicillin-susceptible clones. Hence, serotype 19A replacement occurs, although it is not driven by antibiotic selection pressure.
摘要
在广泛使用7价肺炎球菌结合疫苗（PCV7）后，侵袭性肺炎球菌疾病中出现了血清型替换现象。在一些国家，替换主要由对青霉素不敏感的19A血清型主导。有人提出抗生素选择压力与免疫接种相互作用，导致快速替换。在挪威，抗生素处方受到限制，PCV7接种后19A血清型的替换主要由对青霉素敏感的克隆主导。因此，尽管血清型19A的替换并非由抗生素选择压力驱动，但这种替换仍会发生。
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Eur J Clin Microbiol Infect Dis. 2012 Jun;31(6):1009-13. doi: 10.1007/s10096-011-1399-3. Epub 2011 Sep 8.
2
Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study.英格兰和威尔士 7 价肺炎球菌结合疫苗接种 4 年后的群体免疫和血清型转变：一项观察性队列研究。
Lancet Infect Dis. 2011 Oct;11(10):760-8. doi: 10.1016/S1473-3099(11)70090-1. Epub 2011 May 27.
3
Shifting genetic structure of invasive serotype 19A pneumococci in the United States.美国侵袭性 19A 型肺炎球菌遗传结构的转变。
J Infect Dis. 2011 May 15;203(10):1360-8. doi: 10.1093/infdis/jir052. Epub 2011 Mar 11.
4
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5
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6
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