Department of Surgery, JSDF Kumamoto Hospital, 15-1 Higashihonmachi, Kumamoto, 862-0902, Japan.
Surg Today. 2012 Feb;42(3):280-4. doi: 10.1007/s00595-011-0063-y. Epub 2012 Jan 13.
Mucocele-like tumors (MLTs) of the breast are rare, with only 11 cases reported from Japan and 35 cases from other countries. MLTs of the breast were first described by Rosen in 1986. They are believed to be related to atypical ductal hyperplasia, ductal carcinoma, or mucinous carcinoma. It is difficult to diagnose this tumor preoperatively, and especially difficult to differentiate between benign and malignant forms. We report a case of MLT associated with ductal carcinoma in situ, which was initially diagnosed as fibroadenoma by mammography and ultrasonography, and as mucinous carcinoma by fine-needle aspiration cytology. We discuss the characteristic findings of imaging and the appropriate clinical treatment of this tumor. The characteristic image first signals the possibility of this tumor, following which the diagnosis can be confirmed by pathological examination of a fully excised tumor specimen. Breast-conserving surgery is recommended because of the low risk of high-grade malignancy, even when malignancy is confirmed, and lymph node dissection may be avoided.
乳腺黏液性囊腺瘤样肿瘤（MLTs）罕见，日本报道 11 例，其他国家报道 35 例。乳腺 MLTs 由 Rosen 于 1986 年首次描述。据信，它们与非典型性导管增生、导管癌或黏液癌有关。术前诊断该肿瘤困难，尤其是鉴别良恶性困难。我们报告了一例乳腺 MLT 伴原位导管癌，术前乳腺 X 线摄影和超声检查诊断为纤维腺瘤，细针抽吸细胞学检查诊断为黏液癌。我们讨论了该肿瘤的影像学特征表现和适当的临床治疗。典型的影像学表现首先提示该肿瘤的可能性，然后通过对完全切除的肿瘤标本进行病理检查可确诊。由于高级别恶性肿瘤的风险较低，即使证实为恶性肿瘤，也推荐保乳手术，且可避免淋巴结清扫。
