Dang Brittany Q, Miles Brittany, Young Peter, He Jing, Nguyen Quan D
Radiology, University of Texas Medical Branch, Galveston, USA.
Pathology, University of Texas Medical Branch, Galveston, USA.
Cureus. 2023 Apr 19;15(4):e37829. doi: 10.7759/cureus.37829. eCollection 2023 Apr.
Mucocele-like lesions (MLLs) of the breast are rare neoplasms characterized by dilated, mucin-filled epithelial ducts or cysts that can rupture and expel their contents into the surrounding stroma. They are frequently associated with atypia, dysplastic change, and, more recently, pre-malignant and malignant conditions like atypical ductal hyperplasia, ductal carcinoma, invasive carcinoma, or mucinous carcinoma. The malignant potential of MLLs is often challenging to determine from the initial histologic evaluation of a core-needle biopsy due to copious mucin and low cellularity. Therefore, at initial presentation, MLLs should be surgically excised and thoroughly evaluated for malignancy. In this paper, we present a rare case of an MLL and explore the radiology, histology, carcinogenic potential, diagnostic evaluation, and suggested management of the condition.
乳腺黏液囊肿样病变(MLLs)是罕见的肿瘤,其特征为扩张的、充满黏液的上皮导管或囊肿,这些导管或囊肿可能破裂并将其内容物排入周围的间质。它们常伴有异型性、发育异常改变,以及最近发现的如非典型导管增生、导管癌、浸润性癌或黏液癌等癌前和恶性病变。由于黏液丰富且细胞含量低,MLLs的恶性潜能通常难以通过粗针活检的初始组织学评估来确定。因此,在初次就诊时,MLLs应手术切除并进行全面的恶性评估。在本文中,我们报告了一例罕见的MLL病例,并探讨了该疾病的放射学、组织学、致癌潜能、诊断评估及建议的治疗方法。