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正电子发射断层扫描在精神障碍中的应用。

Positron emission tomography in psychiatric disorders.

机构信息

Department of Emergency Medicine and Radiology, Thomas Jefferson University, 1015 Chestnut Street, Suite 412, Philadelphia, PA 19107, USA.

出版信息

Ann N Y Acad Sci. 2011 Jun;1228:E13-25. doi: 10.1111/j.1749-6632.2011.06162.x.

Abstract

Positron emission tomography (PET) has been widely used in the study of psychiatric disorders. It has been used most extensively in research to determine pathophysiology as well as prognostic and diagnostic information, and response to various interventions in different psychiatric disorders. PET imaging has also been used in the clinical setting, although primarily to help differentiate or diagnose specific disorders. With the continued development of a large array of radiopharmaceuticals that can evaluate all of the components of different neurotransmitter systems (such as serotonin and dopamine), PET imaging will continue to play a key role in research and clinical applications for psychiatric disorders.

摘要

正电子发射断层扫描(PET)已广泛应用于精神疾病的研究。它在研究中被广泛用于确定病理生理学以及预后和诊断信息,以及对不同精神疾病的各种干预措施的反应。PET 成像也已用于临床环境中,尽管主要是帮助区分或诊断特定疾病。随着可评估不同神经递质系统(如 5-羟色胺和多巴胺)所有成分的大量放射性药物的不断发展,PET 成像将继续在精神疾病的研究和临床应用中发挥关键作用。

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