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移民、社会环境与精神障碍发病。

Immigration, social environment and onset of psychotic disorders.

机构信息

Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Canada.

出版信息

Curr Pharm Des. 2012;18(4):518-26. doi: 10.2174/138161212799316028.

Abstract

The recent decade has been characterized by a resurging interest for socio-environmental determinants of psychotic disorders, largely as a result of findings from studies of migration and psychotic disorders. This contribution reviews recent meta-analytic findings which confirm higher incidence rates of schizophrenia and related disorders among first- and second-generation immigrants than in non-immigrant populations, as well as substantial risk variation according to both ethnic minority groups and host society contexts. The relevance of social contexts in the onset of psychosis is also suggested by incidence variation according to the neighbourhood level ethnic density. While limited, an emerging literature suggests potential variations in psychotic-like experiences and at-risk mental states according to ethnic minority status. We then discuss the meaning of findings from migrant studies, as well as integrative models that attempt to account for ethnic variations in the incidence of psychosis and psychotic-like phenomena. In conclusion, there remain numerous gaps in our understanding of the relation between migration, ethnicity, social contexts and the onset of psychosis and we propose future research avenues to address these. In particular, there is a need for multilevel approaches integrating disciplines and methodologies across the psychosis continuum.

摘要

近十年来,人们对精神障碍的社会环境决定因素重新产生了兴趣,这主要是由于移民和精神障碍研究的结果。这篇综述回顾了最近的荟萃分析结果,这些结果证实了第一代和第二代移民的精神分裂症和相关障碍的发病率高于非移民人群,而且根据少数族裔群体和宿主社会环境的不同,风险也有很大的差异。精神病发病的社会环境的相关性也可以根据社区的种族密度的发病率变化来证明。虽然有限,但越来越多的文献表明,根据少数族裔地位,可能会出现类似精神病的体验和高危精神状态的变化。然后,我们讨论了移民研究结果的意义,以及试图解释精神病和类似精神病现象发病率的种族差异的综合模型。总之,我们对移民、族裔、社会环境与精神病发病之间的关系仍有许多不了解的地方,我们提出了未来研究这些问题的途径。特别是需要采用跨精神病学连续体整合学科和方法的多层次方法。

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