Schramek S, Brezina R, Kazár J
Acta Virol. 1977 Sep;21(5):439-41.
A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties such as toxicity for actinomycin D-treated mice, pyrogenicity for rabbits and guinea pigs, ability to elicit hypothermia in white rats and local Schwartzman reaction and active cutaneous anaphylaxis in rabbits.
通过苯酚萃取从斑疹伤寒群立克次体的纯化悬液中分离出一种亲脂性耐热脂多糖(LPS)复合物。该LPS复合物具有抗原性,并具有一些内毒素特性,如对放线菌素D处理的小鼠有毒性、对兔和豚鼠有热原性、能引起白鼠体温过低以及在兔中引发局部施瓦茨曼反应和主动皮肤过敏反应。