Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield, UK.
Clin Hemorheol Microcirc. 2012;51(1):69-75. doi: 10.3233/CH-2011-1510.
This study investigated changes incurred in cutaneous skin blood flux (SKBF) in the superficial veins of the lower limb by upper limb exercise training in the form of arm-cranking in 14 healthy participants over the age of 50 years. Changes in cutaneous microvascular function of the lower leg were assessed using laser Doppler Flowmetry (LDF) during a 30-minute exercise session undertaken over 4-exercise periods. Both SKBF and Time to reach Peak Perfusion (Tmax) were improved significantly during the 2nd (e.g. 121 (± 107.2) vs 280 (± 269.1) and 171 (± 34.4) vs. 247 (± 38.3) respectively) when compared to the first exercise period, while values approaching initial levels in the following stages. The results indicate that the thermoregulatory and vasodilation mechanisms observed during exercise in middle-aged and older healthy people are different to the one appearing in younger age groups, suggesting a more extensive effect of the age-related structural changes than it was previously thought.
本研究调查了上肢运动训练（形式为手臂转动）对上了年纪（50 岁以上）的 14 名健康参与者下肢浅静脉皮肤血流通量（SKBF）的影响。在 4 个运动阶段的 30 分钟运动过程中，使用激光多普勒流量测定法（LDF）评估小腿皮肤微血管功能的变化。与第一运动阶段相比，第二运动阶段的 SKBF 和达到灌注峰值时间（Tmax）均显著提高（例如，121（±107.2）vs 280（±269.1）和 171（±34.4）vs. 247（±38.3）），而在后续阶段，数值接近初始水平。研究结果表明，中老年人运动期间观察到的热调节和血管舒张机制与年轻年龄组的不同，这表明与年龄相关的结构变化的影响比之前认为的更为广泛。
