Tsvirenko S V, Sharavara A A, Iushkov V G, Iastrebov A P
Biull Eksp Biol Med. 1990 Jul;110(7):29-30.
The authors studied medullary glucosaminoglycans of rats and mice in extreme effects (hypoxia, hyperbaric oxygenation, inflammation, radiation, cooling, hemorrhage). Four types of reaction were determined which cause different changes of proliferation of hematopoietic cells. Hematopoiesis stimulation is accompanied by regular change of types of reaction of hematopoietic microenvironment. Its disturbance affects the changes of hematopoiesis and blood regeneration rate. It was shown that the increase of neutral glucosaminoglycans concentrations in bone marrow depended on the play ground and proliferative activity of erythroid sprout and that of acid glucosaminoglycans--primarily of granulocytic sprout.
作者研究了大鼠和小鼠在极端情况下（缺氧、高压氧、炎症、辐射、冷却、出血）的髓质葡糖胺聚糖。确定了四种反应类型，它们会导致造血细胞增殖的不同变化。造血刺激伴随着造血微环境反应类型的规律性变化。其紊乱会影响造血和血液再生率的变化。结果表明，骨髓中中性葡糖胺聚糖浓度的增加取决于红系芽的活动场所和增殖活性，而酸性葡糖胺聚糖的增加主要取决于粒系芽的活动场所和增殖活性。
