Kaliuzhnyĭ L V, Fedoseeva O V
Biull Eksp Biol Med. 1990 Jul;110(7):3-5.
In unanaesthetized rabbits auriculo-acupuncture electrostimulation with frequency of 15 Hz decreased the amplitude of somatosensory EP second component in response to the tooth pulp electrostimulation which was blocked by intravenous injection of naloxone but not by intraventricular injection of saralasin. The same effect of auriculo-acupuncture electrostimulation with frequency 100 Hz was blocked by saralasin, was increased by angiotensin II, was diminished by methysergide but wasn't changed by naloxone. It's suggested that there is angiotensinergic antinociceptive mechanism of dental pain which is activated by auriculo-acupuncture electrostimulation with frequency 100 Hz.
在未麻醉的家兔中,频率为15Hz的耳针电刺激可降低牙髓电刺激诱发的体感诱发电位第二成分的波幅,静脉注射纳洛酮可阻断此效应,而脑室内注射沙拉新则不能。频率为100Hz的耳针电刺激的相同效应可被沙拉新阻断,被血管紧张素II增强,被甲基麦角新碱减弱,但不受纳洛酮影响。提示存在由频率为100Hz的耳针电刺激激活的牙疼痛的血管紧张素能抗痛机制。