Raevskaia O S, Grishanin G G
Biull Eksp Biol Med. 1990 Oct;110(10):339-41.
Auriculo-acupuncture electrostimulation (AES) (15 H2) decreased the amplitude of somatosensory evoked potential (EP) in response to tooth pulp electrostimulation in 64% of acupuncture-sensitive unanesthetized rabbits and didn't induce the changes of EP in 36% of animals (acupuncture-resistant rabbits). The systemic naloxone (0.2 mg/kg) injection reversed the AES analgetic effect and induced the hyperalgesic one in acupuncture-sensitive rabbits but induced the analgetic effect in acupuncture-resistant animals. It has been suggested that the differences of individual characteristics of endogenous opioid system determined different naloxone action in acupuncture-sensitive and acupuncture-resistant rabbits.
耳针电刺激（AES）（15赫兹）可使64%对针刺敏感的未麻醉家兔在牙髓电刺激时体感诱发电位（EP）的波幅降低，而在36%的动物（针刺耐受家兔）中未引起EP变化。全身注射纳洛酮（0.2毫克/千克）可逆转AES的镇痛作用，并在针刺敏感家兔中诱发痛觉过敏，但在针刺耐受动物中诱发镇痛作用。有人提出，内源性阿片系统个体特征的差异决定了纳洛酮在针刺敏感和针刺耐受家兔中的不同作用。
