人类白细胞抗原1990年
HLA 1990.
作者信息
Mayr W R
机构信息
Institute for Transfusion Medicine, Rheinisch-Westfälische Technische Hochschule, Aachen, Federal Republic of Germany.
出版信息
Blut. 1990 Oct;61(4):207-12. doi: 10.1007/BF01744132.
PMID:2224142
Abstract
The HLA system encompasses approximately one thousandth of the human genome and contains a series of closely linked loci coding for molecules which provide the context for the recognition of antigens by T lymphocytes. Within the HLA system, several phenotypically expressed and genomic polymorphisms can be distinguished. These polymorphisms are described and the main objectives for the future research are discussed.
摘要
人类白细胞抗原（HLA）系统约占人类基因组的千分之一，包含一系列紧密连锁的基因座，这些基因座编码的分子为T淋巴细胞识别抗原提供了背景。在HLA系统中，可以区分出几种表型表达和基因组多态性。本文描述了这些多态性，并讨论了未来研究的主要目标。
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