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Patterns of contact phase proteins indicating neuropathy in diabetic patients.

作者信息

Meier P, Marbet G A, Berger W, Duckert F, Friedli W

机构信息

Coagulation and Fibrinolysis Laboratory, Kantonsspital, Basel, Switzerland.

出版信息

Blut. 1990 Oct;61(4):222-5. doi: 10.1007/BF01744135.

DOI:10.1007/BF01744135
PMID:2224144
Abstract

In 42 outpatients of the diabetology division, coagulation and fibrinolysis variables were determined in order to detect typical patterns of results with which it was possible to discriminate between three groups with different diabetic complications (17: no complication, 7: angiopathy alone, 18: neuropathy with or without other complications). There was a statistically significant discriminatory function involving C1-inhibitor concentration, high molecular weight kininogen coagulant activity and fibrinogen as the most decisive variables. The neuropathy group was appropriately separated from the others with an 81% correct reclassification. Heparin cofactor II, histidine-rich glycoprotein, alpha 2-macroglobulin, pre-kallikrein and factor XII had no discriminative power.

摘要

相似文献

1
Patterns of contact phase proteins indicating neuropathy in diabetic patients.
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2
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3
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本文引用的文献

1
[Rapid physiological coagulation method in determination of fibrinogen].[快速生理凝血法测定纤维蛋白原]
Acta Haematol. 1957 Apr;17(4):237-46. doi: 10.1159/000205234.
2
Contact phase of blood coagulation in diabetes mellitus.
Eur J Clin Invest. 1982 Aug;12(4):307-11. doi: 10.1111/j.1365-2362.1982.tb02237.x.
3
Diagnosis and management of diabetic autonomic neuropathy.糖尿病性自主神经病变的诊断与管理
Br Med J (Clin Res Ed). 1982 Oct 2;285(6346):916-8. doi: 10.1136/bmj.285.6346.916.
4
Cleavage of human high molecular weight kininogen markedly enhances its coagulant activity. Evidence that this molecule exists as a procofactor.人高分子量激肽原的裂解显著增强其凝血活性。该分子作为前辅因子存在的证据。
J Clin Invest. 1984 Apr;73(4):954-62. doi: 10.1172/JCI111319.
5
Heparin cofactor II determination--levels in normals and patients with hereditary antithrombin III deficiency and disseminated intravascular coagulation.肝素辅因子II测定——正常人群、遗传性抗凝血酶III缺乏症患者及弥散性血管内凝血患者的水平
Thromb Haemost. 1984 Oct 31;52(2):112-6.
6
Diabetic neuropathy.糖尿病性神经病变
Ann Neurol. 1984 Jan;15(1):2-12. doi: 10.1002/ana.410150103.
7
Platelet aggregation, beta-thromboglobulin and platelet factor 4 in diabetes mellitus and in patients with vasculopathy.糖尿病及血管病变患者的血小板聚集、β-血小板球蛋白和血小板第4因子
Thromb Haemost. 1984 Dec 29;52(3):236-9.
8
The contact phase of blood coagulation in diabetes mellitus and in patients with vasculopathy.糖尿病及血管病变患者的血液凝固接触相。
Thromb Haemost. 1984 Dec 29;52(3):221-3.
9
Fifteen coagulation and fibrinolysis parameters in diabetes mellitus and in patients with vasculopathy.糖尿病及血管病变患者的十五项凝血和纤溶参数
Thromb Haemost. 1984 Oct 31;52(2):138-43.
10
Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies.在含有抗体的琼脂糖凝胶中通过电泳对蛋白质进行定量估计。
Anal Biochem. 1966 Apr;15(1):45-52. doi: 10.1016/0003-2697(66)90246-6.