Friends Research Institute, Inc., Baltimore, MD 21201, USA.
Am J Drug Alcohol Abuse. 2012 Jul;38(4):328-33. doi: 10.3109/00952990.2011.643993. Epub 2012 Jan 13.
Relatively limited empirical evidence exists comparing the impact on HIV sex risk behavior for patients admitted to methadone treatment programs (MTPs) as compared with nontreatment seekers.
This longitudinal cohort study examined HIV sex-risk behavior among 164 out-of-treatment heroin-dependent adults recruited from the street and 351 newly admitted MTP patients. The AIDS Risk Assessment was administered at baseline, 6 months, and 12 months. Generalized linear mixed model and generalized estimating equation analyses were used to examine the changes in sex risk behavior over time.
The participants mean age was 41.5 years, 74.8% were African-American, 24.3% were White, and 54.4% were men. There were no significant differences between the groups in age, race, or gender. At baseline, the out-of-treatment group compared with the in-treatment group reported more sex partners (p < .001) and higher frequency of sex (p = .001). There was a group x time interaction for three of the sex-risk items and the out-of-treatment group reported having significantly more sex partners at both follow-up time points and having significantly more frequent unprotected sex while high at 6 months (all values of p < .01).
Nontreatment seekers are at higher HIV risk than those entering MTPs and should be a focus of sex-risk reduction interventions, even if they are not interested in treatment at that time.
与未接受治疗的寻求者相比,接受美沙酮治疗项目(MTP)的患者的 HIV 性风险行为的影响方面,经验证据相对有限。
这项纵向队列研究调查了 164 名从街头招募的未经治疗的海洛因依赖成年人和 351 名新入院的 MTP 患者的 HIV 性风险行为。在基线、6 个月和 12 个月时进行了艾滋病风险评估。使用广义线性混合模型和广义估计方程分析来检查性风险行为随时间的变化。
参与者的平均年龄为 41.5 岁,74.8%为非裔美国人,24.3%为白人,54.4%为男性。两组在年龄、种族或性别方面没有显著差异。在基线时,与治疗组相比,未经治疗组报告的性伴侣更多(p <.001),性行为频率更高(p =.001)。在三个性风险项目中有一个组 x 时间的交互作用,未经治疗组在两个随访时间点报告的性伴侣更多,并且在 6 个月时高频率的无保护性行为更多(所有 p 值均<.01)。
与那些进入 MTP 的人相比,未经治疗的寻求者处于更高的 HIV 风险之中,即使他们当时对治疗不感兴趣,也应该成为减少性风险干预的重点。