美沙酮维持治疗的中期效果对 HIV 风险行为的影响。
Impact of interim methadone maintenance on HIV risk behaviors.
机构信息
Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
出版信息
J Urban Health. 2010 Jul;87(4):586-91. doi: 10.1007/s11524-010-9451-7.
Abstract
The extent to which interim methadone (IM) without counseling reduces HIV risk behavior has not been reported. The AIDS Risk Assessment scale was administered at baseline and 4-month follow-up to 319 adult heroin-dependent participants randomly assigned to IM or waiting list. On an intent-to-treat basis, there was a significantly greater reduction in drug injection and unprotected sex while high from baseline to follow-up, favoring the IM condition. Remedying the shortage of methadone capacity through the expansion of IM would be a worthwhile approach to reducing the spread of HIV infection.
摘要
尚未有研究报告表明，不进行咨询的美沙酮临时治疗（IM）在多大程度上减少了艾滋病毒高危行为。319 名成年海洛因依赖者被随机分配到美沙酮临时治疗或候补名单，在基线和 4 个月随访时使用艾滋病风险评估量表进行评估。基于意向治疗，与候补名单组相比，美沙酮临时治疗组在随访时从基线开始药物注射和无保护性行为显著减少，这一结果有利于美沙酮临时治疗组。通过扩大美沙酮临时治疗来缓解美沙酮治疗能力的短缺，将是减少艾滋病毒感染传播的一种有价值的方法。
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