Sorensen J L, London J, Heitzmann C, Gibson D R, Morales E S, Dumontet R, Acree M
University of California, San Francisco.
AIDS Educ Prev. 1994 Apr;6(2):95-112.
In two trials of a small-group AIDS prevention approach, 50 methadone maintenance patients and 98 heroin abusers in outpatient detoxification were randomly assigned to experimental or comparison conditions. Experimental condition subjects received a 6-hour, small-group intervention that aimed to improve their knowledge and attitudes about AIDS, skills in syringe sterilization and condom use, and changing high-risk needle use and sexual behaviors. Comparison subjects received a set of written materials about AIDS. At posttest and 3-month follow-ups, experimental condition subjects in both maintenance and detoxification demonstrated greater knowledge of AIDS and risk reduction practices and improved skill in demonstrating condom use. Although outpatient detoxification subjects displayed considerably more risk behaviors at study outset, the intervention's effect appeared to be more robust in methadone maintenance patients. The relative lack of impact on subjects' behaviors points out that more potent, sustained interventions need to be developed to slow the spread of HIV among injecting drug users.
在两项关于小组艾滋病预防方法的试验中,50名美沙酮维持治疗患者和98名门诊戒毒的海洛因滥用者被随机分配到试验组或对照组。试验组受试者接受了一次为时6小时的小组干预,旨在提高他们对艾滋病的知识和态度、注射器消毒及使用避孕套的技能,以及改变高风险的针头使用和性行为。对照组受试者收到了一套关于艾滋病的书面材料。在测试后及3个月的随访中,维持治疗组和戒毒组的试验组受试者对艾滋病和风险降低措施有了更多了解,并且在演示使用避孕套方面的技能有所提高。尽管门诊戒毒受试者在研究开始时表现出更多的风险行为,但该干预措施在美沙酮维持治疗患者中的效果似乎更强。对受试者行为的影响相对不足表明,需要制定更有效的持续干预措施,以减缓艾滋病毒在注射吸毒者中的传播。