Department of Psychiatry, Neurobiology, Pharmacology and Biotecnology, University of Pisa, Pisa, Italy.
Clin Exp Rheumatol. 2011 Nov-Dec;29(6 Suppl 69):S73-8. Epub 2012 Jan 3.
The aim of the present study was to investigate the impact of lifetime potentially traumatic events, including losses, and of post-traumatic stress symptoms on the severity of illness and health-related quality of life in patients with fibromyalgia (FM).
Seventy patients with FM, diagnosed according to the American College of Rheumatology criteria, were consecutively enrolled at the Unit of Rheumatology of the University of Pisa, Italy. Assessments included: SCID-I/P; the Fibromyalgia Impact Questionnaire (FIQ) and the Medical Outcomes Study Short Form-36 Health Survey (MOS SF-36), for the severity of pain; the Health-Related Quality of Life (HRQoL); the Trauma and Loss Spectrum Self-Report (TALS-SR) life-time version.
The FIQ total score was related to the number of loss events (Domain I) and to symptoms of grief reactions (Domain II) and re-experiencing (Domain V) of the TALS-SR. The 'VAS fatigue' scores (FIQ) were significantly related to the TALS-SR symptoms of grief reactions (Domain II) and re-experiencing (Domain V). The Mental Component Summary and Bodily Pain scores of the MOS SF-36 were significantly related to all TALS-SR domains, the latter with the exception of the VIII (Arousal).
Our results corroborate the presence of a relationship between the lifetime exposure to potentially traumatic events, in particular loss events, and lifetime post-traumatic stress symptoms and the severity of illness and HRQoL in patients with FM.
本研究旨在探讨一生中经历的潜在创伤性事件（包括丧失）以及创伤后应激症状对纤维肌痛（FM）患者疾病严重程度和健康相关生活质量的影响。
意大利比萨大学风湿病科连续收治了 70 名符合美国风湿病学会标准的 FM 患者。评估包括：SCID-I/P；纤维肌痛影响问卷（FIQ）和健康研究简表 36 项健康调查（MOS SF-36），用于评估疼痛严重程度；健康相关生活质量（HRQoL）；创伤和丧失范围自我报告（TALS-SR）终身版。
FIQ 总分与丧失事件的数量（域 I）以及 TALS-SR 的悲伤反应（域 II）和再体验（域 V）症状有关。FIQ 的“VAS 疲劳”评分与 TALS-SR 的悲伤反应（域 II）和再体验（域 V）症状显著相关。MOS SF-36 的心理成分综合评分和躯体疼痛评分与 TALS-SR 的所有域显著相关，后者除外 VIII（觉醒）。
我们的结果证实了一生中经历潜在创伤性事件（特别是丧失事件）和一生中创伤后应激症状与 FM 患者疾病严重程度和健康相关生活质量之间存在关系。
