阿巴西普和硫代硫酸钠治疗顽固性幼年皮肌炎并发溃疡和钙化。
Abatacept and sodium thiosulfate for treatment of recalcitrant juvenile dermatomyositis complicated by ulceration and calcinosis.
机构信息
Division of Pediatric Rheumatology, Department of Pediatrics, Inova Fairfax Hospital for Children, Fairfax, VA 22031, USA.
出版信息
J Pediatr. 2012 Mar;160(3):520-2. doi: 10.1016/j.jpeds.2011.11.057. Epub 2012 Jan 13.
Abstract
We report the successful use of abatacept and sodium thiosulfate in a patient with severe recalcitrant juvenile dermatomyositis complicated by ulcerative skin disease and progressive calcinosis. This combination therapy resulted in significant reductions in muscle and skin inflammation, decreased corticosteroid dependence, and halted the progression of calcinosis.
摘要
我们报告了一例严重的难治性青少年皮肌炎合并溃疡性皮肤病和进行性钙化病患者使用阿巴西普和硫代硫酸钠成功治疗的案例。这种联合治疗方案显著减轻了肌肉和皮肤炎症，减少了皮质类固醇的依赖，并阻止了钙化病的进展。
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