Kasjanovová D, Baláz V
Výskumného ústavu gerontológie v Malackách.
Bratisl Lek Listy. 1990 Sep;91(9):709-13.
The functional state of thrombocytes was compared in men of three age groups, i.e. below 46 years, within the range of 46 to 59 years, and above 59 years. Thrombocytes of old people were found to be more sensitive to such aggregation inductors as ADP, collagen, arachidonic acid, and adrenaline compared to thrombocytes of subjects from the younger age groups. A further finding was that blood platelets of old men produced significantly greater amount of ATP than recorded in young men and this may account for hyperactivity of thrombocytes in old age.
对三个年龄组的男性，即46岁以下、46至59岁以及59岁以上男性的血小板功能状态进行了比较。结果发现，与年轻年龄组受试者的血小板相比，老年人的血小板对二磷酸腺苷（ADP）、胶原蛋白、花生四烯酸和肾上腺素等聚集诱导剂更为敏感。进一步的发现是，老年男性的血小板产生的三磷酸腺苷（ATP）量明显多于年轻男性，这可能是老年时血小板活性过高的原因。
