Medical Physics Group, Department of Diagnostic and Interventional Radiology I, Jena University Hospital, Friedrich-Schiller-University, Philosophenweg 3, 07743 Jena, Germany.
Neuroimage. 2012 Aug 15;62(2):1311-5. doi: 10.1016/j.neuroimage.2012.01.004. Epub 2012 Jan 8.
The magnetic properties of tissues affect MR images and differences in magnetic susceptibility can be utilized to provide impressive image contrast. Specifically, phase images acquired with gradient echo MRI provide unique and superb contrast which reflects variations in the underlying tissue composition. There is great interest in extracting tissue susceptibility from image data since magnetic susceptibility is an intrinsic tissue property that reflects tissue composition much more closely than MRI phase. Still, this major tissue contrast mechanism is largely unexplored in magnetic resonance imaging because non-conventional reconstruction and dipole deconvolution are required to quantitatively map tissue susceptibility properly. This short review summarizes the current state of susceptibility contrast and susceptibility mapping and aims to identify future directions.
组织的磁特性会影响磁共振成像，而磁化率的差异可用于提供令人印象深刻的图像对比。具体来说，梯度回波 MRI 采集的相位图像提供了独特而出色的对比，反映了组织成分的变化。从图像数据中提取组织磁化率的兴趣很大，因为磁化率是一种内在的组织特性，比 MRI 相位更能反映组织成分。尽管如此，这种主要的组织对比机制在磁共振成像中还在很大程度上未被探索，因为需要非常规的重建和偶极子反卷积才能正确地定量映射组织磁化率。这篇简短的综述总结了磁化率对比和磁化率映射的现状，并旨在确定未来的方向。
