Knipstein Jeffrey A, Ambruso Daniel R
Department of Pediatrics, Division of Hematology/Oncology/BMT, University of Colorado, Aurora †Bonfils Blood Center, Denver, CO, USA.
J Pediatr Hematol Oncol. 2012 Jul;34(5):372-4. doi: 10.1097/MPH.0b013e3182346be1.
Sweet syndrome is characterized by painful, erythematous cutaneous lesions containing neutrophilic infiltrates. Although more commonly seen in adults, Sweet syndrome has also been recognized in several pediatric cases. Two previous cases of pediatric Sweet syndrome and 1 adult case have been described in chronic granulomatous disease (CGD) patients. We report the case of an infant with known CGD who was presented with methicillin-sensitive Staphylococcus aureus lymphadenitis and subsequently developed Sweet syndrome. CGD patients are prone to several disorders of inflammation. This case illustrates that Sweet syndrome may be part of the spectrum of inflammatory conditions to which CGD patients are predisposed.
斯威特综合征的特征为伴有中性粒细胞浸润的疼痛性红斑性皮肤损害。虽然斯威特综合征在成人中更为常见，但在几例儿科病例中也有发现。此前已有两例儿科斯威特综合征病例和一例成人病例在慢性肉芽肿病（CGD）患者中被描述。我们报告了一例已知患有CGD的婴儿病例，该婴儿出现对甲氧西林敏感的金黄色葡萄球菌淋巴结炎，随后发展为斯威特综合征。CGD患者易患多种炎症性疾病。该病例表明，斯威特综合征可能是CGD患者易患的一系列炎症性疾病的一部分。
