Laboratório de Biologia de Insetos, GBG, Universidade Federal Fluminense-UFF, Niterói, RJ, CEP: 24210-130, Brazil.
Sensors (Basel). 2011;11(12):11664-78. doi: 10.3390/s111211664. Epub 2011 Dec 15.
Quantum dots (QDs) are colloidal semiconductor nanocrystals of a few nanometers in diameter, being their size and shape controlled during the synthesis. They are synthesized from atoms of group II-VI or III-V of the periodic table, such as cadmium telluride (CdTe) or cadmium selenium (CdSe) forming nanoparticles with fluorescent characteristics superior to current fluorophores. The excellent optical characteristics of quantum dots make them applied widely in the field of life sciences. Cellular uptake of QDs, location and translocation as well as any biological consequence, such as cytotoxicity, stimulated a lot of scientific research in this area. Several studies pointed to the cytotoxic effect against micoorganisms. In this mini-review, we overviewed the synthesis and optical properties of QDs, and its advantages and bioapplications in the studies about microorganisms such as protozoa, bacteria, fungi and virus.
量子点(Quantum dots,QDs)是直径为数纳米的胶体半导体纳米晶体,其尺寸和形状在合成过程中得到控制。它们是由元素周期表中 II-VI 族或 III-V 族的原子合成的,例如碲化镉(CdTe)或硒化镉(CdSe),形成具有优于现有荧光团的荧光特性的纳米颗粒。量子点的优异光学特性使其在生命科学领域得到广泛应用。量子点的细胞摄取、定位和转位以及任何生物学后果,如细胞毒性,激发了该领域的大量科学研究。一些研究指出了对微生物的细胞毒性作用。在这篇迷你综述中,我们综述了量子点的合成和光学特性,以及其在研究原生动物、细菌、真菌和病毒等微生物方面的优势和生物应用。