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碳量子点(CQDs)或硼化合物能否成为治疗新冠肺炎的终极解决方案?

Can Carbon Quantum Dots (CQDs) or Boron Compounds be an Ultimate Solution for COVID-19 Therapy?

作者信息

Camlik Gamze, Akkol Esra Kupeli, Degim Zelihagul, Degim Ismail Tuncer

机构信息

Department of Pharmaceutical Technology, Faculty of Pharmacy, Biruni University, 34010, Topkapı, İstanbul, Turkey.

Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330, Ankara, Turkey.

出版信息

Iran J Pharm Res. 2021 Fall;20(4):9-20. doi: 10.22037/ijpr.2021.114856.15071.

DOI:10.22037/ijpr.2021.114856.15071
PMID:35194423
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8842608/
Abstract

Severe acute respiratory syndrome (SARS) is an infectious and highly transmissible disease that is affected by SARS coronavirus (SARS-CoV) and for which there are presently no approved treatments. COVID-19 is a new strain of coronavirus that has not been previously identified in humans. It is also a member of the family and known to cause similar illnesses in humans. The last outbreak has been identified as a Pandemic because of COVID-19 infections in humans. This review has been prepared to give some information to readers or scientists about some new generation of boron-doped or boron attached composite quantum dots during the design phase of the drug or drug delivery systems to be developed to combat COVID-19 and to help in the design of new drugs and systems by opening some new horizons. All scientists and researchers must quickly share their ideas and experiences in the fight against COVID-19 to find a better therapy or strategy for humans, and thus we can be successful. In this sense, this review offers readers some new ideas and rational perspectives. In conclusion, boron-containing composite carbon quantum dots appear to be the most suitable delivery system for treating COVID-19 infections especially when they are delivered through the lung.

摘要

严重急性呼吸综合征(SARS)是一种由SARS冠状病毒(SARS-CoV)引起的具有传染性且传播性很强的疾病,目前尚无获批的治疗方法。新型冠状病毒肺炎(COVID-19)是一种此前未在人类中发现的新型冠状病毒毒株。它也是冠状病毒科的成员,已知会在人类中引发类似疾病。由于人类感染COVID-19,最近一次疫情已被确定为大流行。本综述旨在在开发用于对抗COVID-19的药物或药物递送系统的设计阶段,为读者或科学家提供有关一些新一代硼掺杂或硼附着复合量子点的信息,并通过开拓一些新视野来帮助设计新药和新系统。所有科学家和研究人员必须迅速分享他们在抗击COVID-19方面的想法和经验,以便为人类找到更好的治疗方法或策略,从而取得成功。从这个意义上说,本综述为读者提供了一些新的想法和合理的观点。总之,含硼复合碳量子点似乎是治疗COVID-19感染最合适的递送系统,尤其是当它们通过肺部递送时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/8842608/0738cd7e445d/ijpr-20-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/8842608/6a7684a7a040/ijpr-20-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/8842608/0738cd7e445d/ijpr-20-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/8842608/6a7684a7a040/ijpr-20-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/8842608/0738cd7e445d/ijpr-20-9-g002.jpg

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本文引用的文献

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