Choi Bo Kyoung, Yang Soo Hyun, Suh Kang Hum, Hwang Jin Ah, Lee Moon Hyung, Si Won Keun, Kim Ji Ho
Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea.
Chonnam Med J. 2011 Dec;47(3):185-8. doi: 10.4068/cmj.2011.47.3.185. Epub 2011 Dec 26.
Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants, thrombolysis, insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy is not regarded as a curative treatment but can be associated with a reduction in new thrombotic episodes. We experienced a case of acute total occlusion of PVT provoked by protein C and S deficiency syndrome. PVT was completely recanalized with oral anticoagulant therapy following low molecular weight heparin therapy.
门静脉血栓形成(PVT)是一种罕见的静脉血栓形成形式,会影响肝门静脉血流,进而导致门静脉高压。PVT的治疗方法包括抗凝治疗、溶栓治疗、分流置入、搭桥手术和肝移植。单一抗凝治疗不被视为一种根治性治疗方法,但可减少新的血栓形成事件。我们遇到了一例由蛋白C和S缺乏综合征引发的急性完全性PVT病例。在低分子量肝素治疗后,口服抗凝治疗使PVT完全再通。