Metabolic Research Labs, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
J Neuroendocrinol. 2012 Feb;24(2):393-4. doi: 10.1111/j.1365-2826.2011.02254.x.
It is an inescapable fact that obesity results from consuming more energy than you burn. The interesting question, however, is why some people eat more than others? Recent genetic analyses have revealed that variations in the fat mass and obesity-associated (FTO) gene are robustly associated with obesity and increased food intake. This association is replicable across different age groups in multiple populations and attention is now turned to studying the complex biology of FTO.
不可否认的事实是，肥胖是由于摄入的能量超过消耗的能量所致。然而，有趣的问题是为什么有些人比其他人吃得更多？最近的基因分析表明，脂肪质量和肥胖相关（FTO）基因的变异与肥胖和食物摄入增加密切相关。这种关联在多个人群的不同年龄组中都具有可重复性，现在人们开始关注研究 FTO 的复杂生物学。
