Hirata Eunice Sizue, Mesquita Maria Aparecida, Alves Filho Gentil, Camargo Edwaldo Eduardo
Faculdade de Ciências Médicas, Universidade de Campinas (Unicamp), Brazil.
Rev Bras Anestesiol. 2012 Jan-Feb;62(1):39-47. doi: 10.1016/S0034-7094(12)70101-0.
This study had the purpose of studying gastric emptying in patients with chronic renal failure.
Thirty patients with chronic renal failure were studied, 16 in conservative clinical treatment and 14 in hemodialysis for over six months. The control group (CTL) was composed of 18 asymptomatic volunteers. The method of gastric emptying study was scintigraphy. The standardized test meal was an omelet of three chicken eggs prepared with colloidal sulfur marked with 185 MBq of 99m technetium. Gastric retention curves were studied and T½ of gastric emptying was obtained from them. A T½ value corresponding to the average of T½ values of control group plus twice standard deviation was considered nornmal. Statistical tests used were χ(2) and Kruskal-Wallis.
There was no statistically significant difference with regard to total gastric retention curves and T½ of gastric emptying, which was similar in three studied groups. Nine patients had high T½ of gastric emptying, above 125 minutes. These patients were equally distributed among both genders and conservative clinical treatment and hemodialysis groups.
We concluded that gastric retention rate and T½ of gastric emptying in patients with chronic renal failure in conservative clinical treatment and hemodialysis does not differ from the healthy patients group. Hemodialysis does not seem to reduce the risk of gastric retention in patients with chronic renal failure.
本研究旨在探讨慢性肾衰竭患者的胃排空情况。
对30例慢性肾衰竭患者进行研究，其中16例接受保守临床治疗，14例接受血液透析超过6个月。对照组（CTL）由18名无症状志愿者组成。胃排空研究方法为闪烁扫描法。标准化测试餐是用标记有185MBq的99m锝的胶体硫制备的三个鸡蛋的煎蛋卷。研究胃潴留曲线，并从中获得胃排空的T½。将对应于对照组T½值平均值加两倍标准差的T½值视为正常。所用统计检验为χ(2)检验和Kruskal-Wallis检验。
在总胃潴留曲线和胃排空的T½方面，三个研究组之间没有统计学上的显著差异，情况相似。9例患者胃排空的T½较高，超过125分钟。这些患者在性别以及保守临床治疗组和血液透析组中分布均匀。
我们得出结论，保守临床治疗和血液透析的慢性肾衰竭患者的胃潴留率和胃排空的T½与健康患者组没有差异。血液透析似乎并未降低慢性肾衰竭患者胃潴留的风险。
