Bird N J, Streather C P, O'Doherty M J, Barton I K, Gaunt J I, Nunan T O
Department of Nuclear Medicine, St Thomas' Hospital, London, UK.
Nephrol Dial Transplant. 1994;9(3):287-90.
Radionuclide gastric emptying studies were carried out on 20 patients with end-stage renal failure (ESRF) undergoing continuous ambulatory peritoneal dialysis (CAPD). Nine of the patients had diabetes mellitus. Eight normal volunteers were also studied to establish normal ranges. Solid and liquid emptying patterns were investigated simultaneously using a meal made up of a solid phase labelled with 99mTechnetium and a liquid phase labelled with 111Indium. The solid emptying fitted a model with a lag phase followed by a linear emptying phase and the liquid emptying fitted a single exponential. Nine of the 20 patients (four diabetic, five non-diabetic) were found to have delayed solid emptying, and four of these (two diabetic, two non-diabetic) also had delayed liquid emptying. No correlation was found between any of the parameters studied and the clinical symptoms of the patients. It is concluded that almost half of the patients studied had abnormal gastric emptying, but that many of these did not suffer from severe symptoms.
对20例接受持续性非卧床腹膜透析（CAPD）的终末期肾衰竭（ESRF）患者进行了放射性核素胃排空研究。其中9例患者患有糖尿病。还对8名正常志愿者进行了研究以确定正常范围。使用由99m锝标记的固相和111铟标记的液相组成的餐食同时研究固体和液体排空模式。固体排空符合一个具有延迟期随后是线性排空期的模型，液体排空符合单指数模型。20例患者中有9例（4例糖尿病患者，5例非糖尿病患者）出现固体排空延迟，其中4例（2例糖尿病患者，2例非糖尿病患者）也有液体排空延迟。在所研究的任何参数与患者的临床症状之间均未发现相关性。结论是，几乎一半的研究患者存在胃排空异常，但其中许多患者并未出现严重症状。
