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开发制剂以改善芳樟醇的控制释放,将其用作杀虫剂。

Development of formulations to improve the controlled-release of linalool to be applied as an insecticide.

机构信息

Instituto Murciano de Investigación y Desarrollo Agrario y Alimentario (IMIDA), Murcia, Spain.

出版信息

J Agric Food Chem. 2012 Feb 8;60(5):1187-92. doi: 10.1021/jf204242x. Epub 2012 Jan 27.

DOI:10.1021/jf204242x
PMID:22250856
Abstract

In recent studies, insecticide activity of a monoterpene, linalool, has been demonstrated, finding, however, limitations in application because of its rapid volatilization. Potential effectiveness of microcapsules and effects of various types of matrices on its stability as controlled-release systems for the slow volatilization of linalool to be applied as insecticide were evaluated. To study controlled-release, linalool was entrapped into microcapsules, inclusion complexes, and beads, obtained by different methods, inverse gelation (IG1, IG2, IG3, IG4, and IG5), oil-emulsion-entrapment (OEE), interfacial coacervation (INCO), and chemical precipitation (Cyc5 and Cyc10). The encapsulation yield turned out to be different for each formulation, reaching the maximum retention for IG1 and OEE. In controlled-release, OEE followed by INCO presented a long time necessary for releasing as a result of the presence of glycerol or chitosan. These results pointed out remarkable differences in the release behavior of linalool depending on matrix composition and the method of encapsulation.

摘要

在最近的研究中,证明了单萜化合物芳樟醇具有杀虫剂活性,但由于其快速挥发,在应用中存在局限性。评估了微胶囊化的潜在效果以及各种类型基质对其作为杀虫剂缓慢挥发的控释系统的稳定性的影响。为了研究控释,将芳樟醇包封到微胶囊、包合物和珠粒中,这些珠粒通过不同的方法获得,包括反向凝胶化(IG1、IG2、IG3、IG4 和 IG5)、油乳液包封(OEE)、界面凝聚(INCO)和化学沉淀(Cyc5 和 Cyc10)。结果表明,每种配方的包封产率都不同,IG1 和 OEE 的保留率最高。在控释中,OEE 随后是 INCO,由于甘油或壳聚糖的存在,需要很长时间才能释放。这些结果表明,芳樟醇的释放行为取决于基质组成和包封方法,存在显著差异。

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