Department of Maternal and Pediatric Sciences, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Hum Vaccin Immunother. 2012 Jan;8(1):17-20. doi: 10.4161/hv.8.1.18145. Epub 2012 Jan 1.
Influenza is frequent among otherwise healthy day-care and school-aged children. Recent studies have demonstrated its significant effect on various outcome factors, including significantly more school and parental work absenteeism, and secondary illnesses among family members. Other studies have shown that the potential benefit of vaccinating children against influenza extends to other members of their families, thus supporting earlier economic modeling analyses of immunization programs. Although there are some differences in the clinical and socio-economic impact of seasonal and pandemic influenza, the benefits of vaccination are similar in both cases. The vaccination of otherwise healthy children may significantly reduce direct and indirect influenza-related costs, which supports the recommendation to make wider use of influenza vaccine in healthy children of any age in order to reduce the burden of infection on the community.
流感在健康的日托儿童和学龄儿童中很常见。最近的研究表明，它对各种结果因素有显著影响，包括儿童及其家庭成员的缺勤率显著增加，以及家庭成员中的继发疾病。其他研究表明，为儿童接种流感疫苗对其家庭成员也有潜在益处，从而支持对免疫接种计划进行早期经济建模分析。虽然季节性流感和大流行性流感在临床和社会经济影响方面存在一些差异，但接种疫苗的益处是相似的。为健康儿童接种疫苗可以显著降低直接和间接与流感相关的成本，这支持了在任何年龄段的健康儿童中更广泛使用流感疫苗的建议，以减轻社区感染负担。
