Rouland J F, Hochart G, Constantinides G
Bull Soc Ophtalmol Fr. 1990 Jun-Jul;90(6-7):643-4.
Retinochoroidal coloboma results from an incomplete closure of the ocular embryonic fissure. Uni or bilateral, the coloboma can be associated with cataract, microphthalmia, retinal detachment... but rarely with neovascularization. This association is comparable with subretinal neovascularization in high myopia, angioid streaks, choroiditis and choroidal ruptures. The disruption of the normal anatomy of the Bruch's membrane is a possible entry site of choroidal blood vessels. But the reason why only rare cases are reported is unknown.
视网膜脉络膜缺损是由于眼胚胎裂闭合不全所致。缺损可为单侧或双侧，可伴有白内障、小眼球、视网膜脱离……但很少伴有新生血管形成。这种关联与高度近视、血管样条纹、脉络膜炎和脉络膜破裂中的视网膜下新生血管形成类似。 Bruch膜正常解剖结构的破坏可能是脉络膜血管的进入部位。但为何仅报道了少数病例尚不清楚。
