雷珠单抗治疗儿童与脉络膜缺损相关的脉络膜新生血管膜

Ranibizumab for coloboma-related choroidal neovascular membrane in a child.

作者信息

Goodwin Peter, Shields Carol L, Ramasubramanian Aparna, Brown Gary C, Shields Jerry A

机构信息

Ocular Oncology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA.

出版信息

J AAPOS. 2009 Dec;13(6):616-7. doi: 10.1016/j.jaapos.2009.09.009.

DOI:10.1016/j.jaapos.2009.09.009

PMID:20006832

Abstract

Optic nerve and retinochoroidal coloboma are caused by incomplete closure of the embryonic fissure during fetal development.(1) Affected patients carry a risk for retinal detachment and less so for choroidal neovascular membranes (CNVM) secondary to the altered anatomy. Because of the rarity of this condition and the even more unusual occurrence of such complications, there are only a few case reports on the treatment of coloboma-related CNVM. Herein we report the results of ranibizumab and laser photocoagulation for coloboma-related CNVM in a child.

摘要

视神经和视网膜脉络膜缺损是由胎儿发育期间胚胎裂孔不完全闭合引起的。（1）受影响的患者有视网膜脱离的风险，继发于解剖结构改变的脉络膜新生血管膜（CNVM）的风险相对较小。由于这种疾病罕见，此类并发症的发生更为罕见，因此关于治疗缺损相关CNVM的病例报告很少。在此，我们报告了一名儿童使用雷珠单抗和激光光凝治疗缺损相关CNVM的结果。