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Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols.

作者信息

Li Yuanpei, Xiao Wenwu, Xiao Kai, Berti Lorenzo, Luo Juntao, Tseng Harry P, Fung Gabriel, Lam Kit S

机构信息

Department of Biochemistry and Molecular Medicine, UC Davis Cancer Center, University of California, Davis, 2700 Stockton Blvd., Sacramento, CA 95817, USA.

出版信息

Angew Chem Int Ed Engl. 2012 Mar 19;51(12):2864-9. doi: 10.1002/anie.201107144. Epub 2012 Jan 17.

DOI:10.1002/anie.201107144
PMID:22253091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3545653/
Abstract
摘要

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8
Intracellularly monitoring/imaging the release of doxorubicin from pH-responsive nanoparticles using Förster resonance energy transfer.利用Förster 共振能量转移，对 pH 响应型纳米颗粒内阿霉素的释放进行细胞内监测/成像。
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