Exercise and Sport Nutrition Laboratory, Department of Health and Kinesiology, Texas A&M University, College Station, TX 77845, USA.
Nutrients. 2010 Jan;2(1):75-98. doi: 10.3390/nu2010075. Epub 2010 Jan 25.
Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation. Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2-6 grams/day) has been shown to increase carnosine concentrations in skeletal muscle by 20-80%. Several studies have reported that β-ALA supplementation can increase high-intensity intermittent exercise performance and/or training adaptations. Although the specific mechanism remains to be determined, the ergogenicity of β-ALA has been most commonly attributed to an increased muscle buffering capacity. More recently, researchers have investigated the effects of co-ingesting β-ALA with creatine monohydrate to determine whether there may be synergistic and/or additive benefits. This paper overviews the theoretical rationale and potential ergogenic value of β-ALA supplementation with or without creatine as well as provides future research recommendations.
肌肽被报道具有作为生理缓冲剂、具有抗氧化特性、影响酶调节以及影响肌浆网钙调节的作用。β-丙氨酸（β-ALA）是一种非必需氨基酸。β-ALA 补充剂（例如，每天 2-6 克）已被证明可使骨骼肌中的肌肽浓度增加 20-80%。多项研究报告称，β-ALA 补充剂可以提高高强度间歇运动的表现和/或训练适应性。尽管具体机制仍有待确定，但 β-ALA 的功效最常归因于肌肉缓冲能力的提高。最近，研究人员研究了同时摄入 β-ALA 和一水肌酸对运动的影响，以确定是否存在协同和/或附加益处。本文综述了补充 β-ALA 或不补充肌酸的理论依据和潜在的功效，并提供了未来的研究建议。
