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使用心脏电生理学多尺度模型预测无处不在的心电图的最佳位置和方向。

Predicting the optimal position and direction of a ubiquitous ECG using a multi-scale model of cardiac electrophysiology.

作者信息

Lim Ki Moo, Hong Seong Bae, Jeon Jae Won, Gyung Min Su, Ko Byung Hoon, Bae Sang Kon, Shin Kun Soo, Shim Eun Bo

机构信息

Department of Mechanical & Biomedical Engineering, Kangwon National University, Chuncheon, Ganwon-do, South Korea.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:993-6. doi: 10.1109/IEMBS.2011.6090230.

Abstract

In this study, we determined the optimal position and direction of a one-channel bipolar electrocardiogram (ECG), used ubiquitously in healthcare. To do this, we developed a three-dimensional (3D) electrophysiological model of the heart coupled with a torso model that can generate a virtual body surface potential map (BSPM). Finite element models of the atria and ventricles incorporated the electrophysiological dynamics of atrial and ventricular myocytes, respectively. The torso model, in which the electric wave pattern on the cardiac tissue is reflected onto the body surface, was implemented using a boundary element method. Using the model, we derived the optimal positions of two electrodes, 5 cm apart, of the bipolar ubiquitous ECG (U-ECG) for detecting the P, R, and T waves. This model can be used as a simulation tool to design U-ECG device for use for various arrhythmia and normal patients.

摘要

在本研究中,我们确定了医疗保健中普遍使用的单通道双极心电图(ECG)的最佳位置和方向。为此,我们开发了一个心脏的三维(3D)电生理模型,并结合一个可以生成虚拟体表电位图(BSPM)的躯干模型。心房和心室的有限元模型分别纳入了心房和心室肌细胞的电生理动力学。躯干模型利用边界元法实现,其中心脏组织上的电波模式反映在体表上。利用该模型,我们推导了用于检测P波、R波和T波的双极通用心电图(U-ECG)中相距5厘米的两个电极的最佳位置。该模型可作为一种模拟工具,用于设计适用于各种心律失常患者和正常患者的U-ECG设备。

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