Pounder R E, Lanzon-Miller S, Smith J T, Gavey C, Nwokolo C U, Prewett E J, Sercombe J
Academic Department of Medicine, Royal Free Hospital, School of Medicine, London, UK.
Dig Dis. 1990;8 Suppl 1:10-7. doi: 10.1159/000171287.
The Royal Free Hospital protocol for simultaneous measurement of 24-hour intragastric acidity and plasma gastrin concentration is described in detail. The methods of analysing such data are discussed, with recommendations for a standard four-way analysis: median hourly 24-hour intragastric acidity or pH, or plasma gastrin concentration; integrated 24-hour intragastric acidity, or plasma gastrin concentration; analysis of integrated values according to meal-related intervals; and quantification of the percentage of time in a 24-hour period that intragastric pH is greater than 3.
详细描述了皇家自由医院同时测量24小时胃内酸度和血浆胃泌素浓度的方案。讨论了分析此类数据的方法，并推荐了一种标准的四向分析方法：24小时胃内酸度或pH值的每小时中位数，或血浆胃泌素浓度；24小时胃内酸度或血浆胃泌素浓度的积分值；根据与进餐相关的时间段对积分值进行分析；以及量化24小时内胃内pH值大于3的时间百分比。
