颅脑损伤患者的高原波与压力感受器反射敏感性：一项病例研究。

Plateau waves and baroreflex sensitivity in patients with head injury: a case study.

作者信息

Shahsavari S, McKelvey T, Ritzén C Eriksson, Rydenhag B

机构信息

Department of Signals and Systems, Signal Processing, Chalmers University of Technology, Sweden.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:3792-5. doi: 10.1109/IEMBS.2011.6090768.

DOI:10.1109/IEMBS.2011.6090768

PMID:22255165

Abstract

The study aimed to investigate baroreceptor reflex sensitivity in a patient with head injury for whom plateau waves of intracranial pressure (ICP) were recorded. Baroreflex sensitivity index was separately estimated on top of plateau waves and during intermediate intervals between two consecutive waves. The EuroBaVar data set was utilized to verify and validate the results. A very high baroreflex sensitivity associated with dominant parasympathetic activity was observed spontaneous to the acute elevations of ICP. The high vagal afferent discharge was found to be suggestive for the high firing rate of carotid baroreceptors and probably an active Cushing reflex mechanism during plateau waves.

摘要

该研究旨在调查一名记录到颅内压（ICP）平台波的头部受伤患者的压力感受器反射敏感性。在平台波顶部以及两个连续波之间的中间间隔期间分别估算压力反射敏感性指数。利用EuroBaVar数据集来验证和确认结果。观察到与主要副交感神经活动相关的非常高的压力反射敏感性是ICP急性升高时自发出现的。发现高迷走神经传入放电提示颈动脉压力感受器的高发放率，并且可能在平台波期间存在活跃的库欣反射机制。