Yamazaki Nozomu, Watanabe Hiroki, Seki Masatoshi, Hoshi Takeharu, Kobayashi Yo, Miyashita Tomoyuki, Fujie Masakatsu G
Graduate School of Science and Engineering, Waseda University, Japan.
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:5753-7. doi: 10.1109/IEMBS.2011.6091424.
Radio frequency ablation (RFA) for lung cancer has increasingly been used over the past few years because RFA is minimally invasive treatment for patients. As a feature of RFA for the lung cancer, lung has the air having low thermal conductivity. Therefore, RFA for lung has the advantage that only the tumor is coagulated because heating area is confined to the immediate vicinity of the heating point. However, it is difficult for operators to control the precise formation of coagulation zones due to inadequate imaging modalities. We propose a method using numerical simulation to analyze the temperature distribution of the organ in order to overcome the current deficiencies. Creating an accurate thermophysical model was a challenging problem because of the complexities of the thermophysical properties of the organ. In this work, as the processes in the development of ablation simulator, measurement of the pressure dependence of lung thermal conductivity and in vitro estimation of the temperature distribution during RFA is presented.
在过去几年中，肺癌的射频消融（RFA）技术越来越多地被使用，因为RFA对患者来说是一种微创治疗方法。作为肺癌RFA的一个特点，肺内含有热导率低的空气。因此，肺部RFA的优势在于，由于加热区域局限于加热点的紧邻区域，所以只有肿瘤会被凝固。然而，由于成像方式不足，操作人员很难精确控制凝固区的形成。为了克服当前的不足，我们提出了一种使用数值模拟来分析器官温度分布的方法。由于器官热物理性质的复杂性，创建一个准确的热物理模型是一个具有挑战性的问题。在这项工作中，作为消融模拟器开发过程的一部分，我们展示了肺热导率对压力依赖性的测量以及RFA期间温度分布的体外估计。
