Czerniawska Ewa, Pogrzebielski Arkadiusz, Romanowska-Dixon Bozena
Z Katedry i Kliniki Okulistyki i Onkologii Okulistycznej Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie.
Klin Oczna. 2011;113(7-9):274-6.
Malherbe's calcifying epithelioma (pilomatrixoma)--is a rare, benign tumor of hair matrix.
Of this study is to present the clinical variability of epithelioma, pathomorfological appearance of the tumor and the views on its pathogenesis.
Malherbe's calcifying epithelioma has a very different, sometimes unusual appearance, similar to other, more frequent laesions. Due to this fact and the rarity of the tumor it is sometimes overlooked in diagnostic considerations, or confused with more common tumors. Genetic analysis at this stage, allows to establish a probable causal relationship between mutations in the beta-catenins coding gene and development of pilomatrixoma. Extremely rare epithelioma may undergo transformation into pilomatrix carcinoma.
The only reliable criterion of diagnosis remains pathological evaluation which despite the deceptive macroscopic appearance of the tumor provides correct diagnosis.
马尔赫布钙化上皮瘤（毛母质瘤）——是一种罕见的毛发基质良性肿瘤。
本研究旨在呈现上皮瘤的临床变异性、肿瘤的病理形态学表现及其发病机制的观点。
马尔赫布钙化上皮瘤外观差异很大，有时不寻常，类似于其他更常见的病变。由于这一事实以及该肿瘤的罕见性，它在诊断考虑中有时会被忽视，或与更常见的肿瘤混淆。现阶段的基因分析有助于确定β-连环蛋白编码基因突变与毛母质瘤发生之间可能的因果关系。极其罕见的上皮瘤可能会转化为毛母质癌。
唯一可靠的诊断标准仍然是病理评估，尽管肿瘤的宏观外观具有欺骗性，但病理评估能提供正确诊断。
