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一例耳廓部发生的马尔赫贝溃疡型钙化上皮瘤患者:病例报告

A patient with ulcerated calcifying epithelioma of Malherbe in the pinna: case report.

作者信息

Upile Tahwinder, Jerjes Waseem, Sipaul Fabian, Sandison Ann, Kafas Panagiotis, Al-Khawalde Mohammed, Radhi Hani

机构信息

Department of Head and Neck Surgery, Chase Farm & Barnet NHS Trust, Enfield, UK.

出版信息

Head Neck Oncol. 2012 May 21;4:25. doi: 10.1186/1758-3284-4-25.

DOI:10.1186/1758-3284-4-25
PMID:22613633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3414780/
Abstract

INTRODUCTION

Although pilomatrixomas are frequently encountered by dermatologists and pathologists in the differential diagnosis of head and neck lesions, this is not usually the case among head and neck surgeons. A pilomatrixoma (calcifying epithelioma of Malherbe) is a benign tumour of the hair matrix cells. Histologically it is characterised by the presence of ghost cells, basophilic cells and foreign body cells. It may sometimes be difficult to histologically distinguish it from its malignant counterpart, the pilomatrix carcinoma. We report an interesting case of an ulcerated pilomatrixoma of the pinna in a middle-aged Caucasian female.

CASE PRESENTATION

A 46-year-old Caucasian female presented with a one-month history of tender brownish lump on the pinna. Initially it was thought to represent a pyogenic granuloma. The lesion was treated by wide circular excision. Histopathological evaluation reported a benign calcifying epithelioma of Malherbe.

CONCLUSION

A search of the world's literature has led us to believe that this is a rare case of a calcifying epithelioma of Malherbe of the pinna. The rapid growth and ulcerative nature of this tumour makes this case even more unique.

摘要

引言

尽管在头颈部病变的鉴别诊断中,皮肤科医生和病理科医生经常会遇到毛母质瘤,但头颈外科医生通常并非如此。毛母质瘤(马尔赫布钙化上皮瘤)是一种毛发基质细胞的良性肿瘤。在组织学上,其特征是存在影细胞、嗜碱性细胞和异物细胞。有时在组织学上很难将其与恶性对应物毛母质癌区分开来。我们报告了一例中年白人女性耳廓溃疡性毛母质瘤的有趣病例。

病例介绍

一名46岁的白人女性,耳廓出现一个有触痛的褐色肿块,病史为一个月。最初认为是化脓性肉芽肿。该病变通过广泛的环形切除进行治疗。组织病理学评估报告为良性马尔赫布钙化上皮瘤。

结论

检索世界文献后,我们认为这是一例罕见的耳廓马尔赫布钙化上皮瘤病例。该肿瘤的快速生长和溃疡性特征使其更为独特。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/458e1e59000a/1758-3284-4-25-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/4d7ea3ae0ec3/1758-3284-4-25-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/c352116150cb/1758-3284-4-25-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/3c40353680a4/1758-3284-4-25-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/458e1e59000a/1758-3284-4-25-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/4d7ea3ae0ec3/1758-3284-4-25-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/c352116150cb/1758-3284-4-25-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/3c40353680a4/1758-3284-4-25-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fc/3414780/458e1e59000a/1758-3284-4-25-4.jpg

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本文引用的文献

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Calcifying epithelioma of Malherbe; report of 15 cases, with comments on its differentiation from calcified epidermal cyst and on its histogenesis.马尔赫贝钙化上皮瘤;15例报告,并论其与钙化表皮样囊肿的鉴别及组织发生
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