National Center for Biomedical Analysis, Army Center for Microbial Detection and Research, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences-AMMS, Beijing, China.
Scand J Immunol. 2012 Jun;75(6):543-52. doi: 10.1111/j.1365-3083.2012.02686.x.
T helper 17 (TH17) cells have well-described roles in autoimmune diseases. The immune modulations of development and function of TH17 have become a key issue. In this review, we summarize the recent findings regarding the direct and indirect signalling regulatory mechanisms of TH17 cells in the general mouse model of autoimmune diseases and other human diseases.
辅助性 T 细胞 17（TH17）在自身免疫性疾病中具有明确的作用。TH17 细胞的发育和功能的免疫调节已成为一个关键问题。在这篇综述中，我们总结了关于在自身免疫性疾病和其他人类疾病的一般小鼠模型中 TH17 细胞的直接和间接信号转导调节机制的最新发现。
