螺内酯 C 的合成研究：探索 23 元全碳大环骨架的形成。
Studies toward the synthesis of spirolide C: exploration into the formation of the 23-membered all-carbon macrocyclic framework.
机构信息
Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.
出版信息
Org Lett. 2012 Feb 3;14(3):804-7. doi: 10.1021/ol203342e. Epub 2012 Jan 19.
Abstract
The synthesis of two complex subunits en route to spirolide C is described. A key alkyllithium addition to an aldehyde joins the fragments, which are advanced in order to investigate a ring-closing metathesis to form the 23-membered all-carbon macrocyclic framework.
摘要
描述了通向螺旋内酯 C 的两个复杂亚基的合成。醛的关键烷基锂加成连接片段，推进这些片段是为了研究闭环复分解反应以形成 23 元全碳大环骨架。
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