Beaumont Stéphane, Ilardi Elizabeth A, Tappin Nicholas D C, Zakarian Armen
Department of Chemistry and Biochemistry, University of California at Santa Barbara, Santa Barbara, CA 93106, USA.
European J Org Chem. 2010 Oct 1;2010(30):5743-5765. doi: 10.1002/ejoc.201000842.
This microreview provides a compilation of synthetic approaches and total syntheses of pinnatoxin A in a survey of the literature up to early 2010. Pinnatoxin A is the first discovered and representative member of a fascinating group of potent marine toxins that share a spiroimine subunit as a unifying structural element.
本微型综述在对截至2010年初的文献进行调研的基础上,汇总了海葵毒素A的合成方法及全合成。海葵毒素A是首批发现的、具有代表性的强效海洋毒素,这类毒素有着迷人的特性,且都含有一个螺亚胺亚基作为统一的结构元素。