Paul Flechsig Institute for Brain Research, Universität Leipzig, Leipzig, Germany.
Biophys J. 2011 Dec 7;101(11):2611-9. doi: 10.1016/j.bpj.2011.09.062.
In vertebrate eyes, images are projected onto an inverted retina where light passes all retinal layers on its way to the photoreceptor cells. Light scattering within this tissue should impair vision. We show that radial glial (Müller) cells in the living retina minimize intraretinal light scatter and conserve the diameter of a beam that hits a single Müller cell endfoot. Thus, light arrives at individual photoreceptors with high intensity. This leads to an optimized signal/noise ratio, which increases visual sensitivity and contrast. Moreover, we show that the ratio between Müller cells and cones-responsible for acute vision-is roughly 1. This suggests that high spatiotemporal resolution may be achieved by each cone receiving its part of the image via its individual Müller cell-light guide.
在脊椎动物的眼睛中，图像被投射到倒置的视网膜上，光线在到达光感受器细胞的过程中穿过所有的视网膜层。光在组织内的散射会损害视力。我们发现，活体视网膜中的放射状胶质（Müller）细胞可最大限度地减少视网膜内的光散射，并保持击中单个 Müller 细胞足突的光束的直径。因此，光以高强度到达单个光感受器。这导致了优化的信号/噪声比，从而提高了视觉灵敏度和对比度。此外，我们发现 Müller 细胞和负责急性视觉的视锥细胞之间的比例大约为 1:1。这表明，每个视锥细胞通过其各自的 Müller 细胞光导接收图像的一部分，可能实现高时空分辨率。
