Kim Jae Jun, Park Jae-Kil, Wang Young-Pil, Choi Soo Hwan, Jo Keon Hyon
Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, Catholic Cancer Center, College of Medicine, The Catholic University of Korea, Korea.
Korean J Thorac Cardiovasc Surg. 2011 Aug;44(4):301-3. doi: 10.5090/kjtcs.2011.44.4.301. Epub 2011 Aug 18.
Sarcoidosis is a somewhat common pulmonary disease, but the concurrence of lung cancer and sarcoidosis in the same patient is very rare. Because sarcoidosis usually presents as mediastinal lymphadenopathies, this concurrence in a lung cancer patient detected radiologically is apt to be misunderstood to be mediastinal metastases, and it is thus considered to be an unresectable disease. We report a case of lung cancer associated with sarcoidosis that developed in a 65-year-old woman who underwent surgery. Radiological studies revealed a 1.9×1.7 cm mass in the left upper lobe with multiple enlarged bilateral mediastinal lymph nodes (2R, 3a, 4R, 4L, 5, 6, 7, 8R). Pathologic findings showed that the mass was a well-differentiated adenocarcinoma and all of the enlarged mediastinal lymph nodes were granulomas without cancer metastasis. We report this case with a review of the literature.
结节病是一种较为常见的肺部疾病,但同一患者同时患有肺癌和结节病的情况非常罕见。由于结节病通常表现为纵隔淋巴结肿大,因此在通过影像学检查发现的肺癌患者中,这种并存情况容易被误解为纵隔转移,进而被认为是不可切除的疾病。我们报告一例65岁女性发生的与结节病相关的肺癌病例,该患者接受了手术。影像学研究显示左上叶有一个1.9×1.7 cm的肿块,双侧纵隔多个淋巴结肿大(2R、3a、4R、4L、5、6、7、8R)。病理结果显示该肿块为高分化腺癌,所有肿大的纵隔淋巴结均为肉芽肿,无癌转移。我们报告此病例并对文献进行回顾。