Ivanoff Chris S, Hottel Timothy L, Tantbirojn Daranee Versluis, Versluis Antheunis, Garcia-Godoy Franklin
Department of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, 875 Union Avenue, Memphis, TN 38163, USA.
Am J Dent. 2011 Dec;24(6):341-5.
To compare both quantitatively and qualitatively, the efficacy of dielectrophoresis to diffusion on the uptake of fluoride by enamel.
A 1.23% APF gel was applied to 16 bovine incisor specimens for 20 minutes by dielectrophoresis or diffusion. Absorption and penetration were evaluated by wavelength dispersive spectrometry.
Fluoride concentrations in the diffusion group were significantly higher than baseline readings at 10 and 20 microm depths; fluoride concentration in dielectrophoretically treated teeth was significantly higher than the diffusion group at 10, 20, and 50 microm (ANOVA/Student-Newman-Keuls post hoc, P = 0.05). Significantly higher fluoride uptake was found with dielectrophoresis compared to passive diffusion at 10, 20, and 50 microm depths (paired t-test, P = 0.05). Dielectrophoresis doubled fluoride uptake in the superficial layers compared to passive diffusion, and drove the fluoride significantly deeper with an uptake six times higher than diffusion at 50 microm depth. Dielectrophoresis enhanced penetration and increased uptake of fluoride on average by 600% at 50 microm. The amount of fluoride delivered at 50 microm was equivalent to long-term exposure of prophylactic fluoride. With proper polarizing frequencies, dielectrophoresis could enhance fluoride delivery into tooth enamel at higher penetration depths and concentrations than diffusion.
从定量和定性两方面比较介电泳和扩散作用对牙釉质摄取氟化物的效果。
将1.23%的酸性磷酸氟（APF）凝胶通过介电泳或扩散作用施加于16个牛切牙标本上20分钟。通过波长色散光谱法评估吸收和渗透情况。
在10微米和20微米深度处，扩散组中的氟化物浓度显著高于基线读数；在10微米、20微米和50微米处，经介电泳处理的牙齿中的氟化物浓度显著高于扩散组（方差分析/Student-Newman-Keuls事后检验，P = 0.05）。在10微米、20微米和50微米深度处，与被动扩散相比，介电泳作用下的氟化物摄取量显著更高（配对t检验，P = 0.05）。与被动扩散相比，介电泳使表层的氟化物摄取量增加了一倍，并使氟化物显著更深地渗透，在50微米深度处的摄取量比扩散高六倍。在50微米处，介电泳增强了渗透并使氟化物摄取量平均增加了600%。在五十微米处输送的氟化物量相当于长期接触预防性氟化物的量。通过适当的极化频率，介电泳可以比扩散作用在更高的渗透深度和浓度下增强氟化物向牙釉质中的输送。
