Department of Pharmacotherapy and Pharmaceutical Care, University of Groningen, The Netherlands.
BMC Public Health. 2012 Jan 20;12:59. doi: 10.1186/1471-2458-12-59.
Reports on the state of knowledge about medicines and driving showed an increased concern about the role that the use of medicines might play in car crashes. Much of patient knowledge regarding medicines comes from communications with healthcare professionals. This study, part of the DRUID (Driving Under the Influence of Drugs, alcohol and medicines) project, was carried out in four European countries and attempts to define predictors for knowledge of patients who use driving-impairing medicines. The influence of socio-demographic variables on patient knowledge was investigated as well as the influence of socio-demographic factors, knowledge and attitudes on patients' reported behaviour regarding driving under the influence of medicines.
Pharmacists handed out questionnaires to patients who met the inclusion criteria: 1) prevalent user of benzodiazepines, antidepressants or first generation antihistamines for systemic use; 2) age between 18 and 75 years old and 3) actual driver of a motorised vehicle. Factors affecting knowledge and reported behaviour towards driving-impairing medicines were analysed by means of multiple linear regression analysis and multiple logistic regression analysis, respectively.
A total of 633 questionnaires (out of 3.607 that were distributed to patients) were analysed. Patient knowledge regarding driving under the influence of medicines is better in younger and higher educated patients. Information provided to or accessed by patients does not influence knowledge. Patients who experienced side effects and who have a negative attitude towards driving under the influence of impairing medicines are more prone to change their driving frequency behaviour than those who use their motorised vehicles on a daily basis or those who use anti-allergic medicines.
Changes in driving behaviour can be predicted by negative attitudes towards driving under the influence of medicines but not by patients' knowledge regarding driving under the influence of medicines. Future research should not only focus on information campaigns for patients but also for healthcare providers as this might contribute to improve communications with patients regarding the risks of driving under the influence of medicines.
关于药物与驾驶的知识状况报告表明,人们越来越关注药物使用可能在车祸中所起的作用。患者对药物的了解大多来自与医疗保健专业人员的沟通。这项研究是 DRUID(药物、酒精和药物对驾驶的影响)项目的一部分,在四个欧洲国家进行,旨在确定使用影响驾驶能力的药物的患者的知识预测因素。研究调查了社会人口统计学变量对患者知识的影响,以及社会人口统计学因素、知识和态度对患者报告的药物影响下驾驶行为的影响。
药剂师向符合以下纳入标准的患者发放问卷:1)正在使用苯二氮䓬类药物、抗抑郁药或第一代全身用抗组胺药的患者;2)年龄在 18 至 75 岁之间;3)实际驾驶机动车辆的患者。通过多元线性回归分析和多元逻辑回归分析,分别分析影响知识和报告行为的因素。
共分析了 633 份问卷(从分配给患者的 3607 份问卷中)。年轻和受教育程度较高的患者对药物影响驾驶的知识更好。向患者提供的信息或患者自行获取的信息并不影响知识。经历过副作用且对药物影响驾驶有负面态度的患者比那些每天使用机动车辆或使用抗过敏药物的患者更有可能改变他们的驾驶频率行为。
可以通过对药物影响驾驶的负面态度来预测驾驶行为的变化,但不能通过患者对药物影响驾驶的知识来预测。未来的研究不仅应关注针对患者的信息宣传活动,还应关注针对医疗保健提供者的宣传活动,因为这可能有助于改善与患者就药物影响驾驶的风险进行沟通。