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检测和分子特征分析奥地利野猪和猎犬中的猪疱疹病毒 1 型。

Detection and molecular characterization of Suid herpesvirus type 1 in Austrian wild boar and hunting dogs.

机构信息

AGES Institute for Veterinary Disease Control Mödling, Robert Koch Gasse 17, A-2340 Mödling, Austria.

出版信息

Vet Microbiol. 2012 Jun 15;157(3-4):276-84. doi: 10.1016/j.vetmic.2011.12.033. Epub 2011 Dec 30.

DOI:10.1016/j.vetmic.2011.12.033
PMID:22264387
Abstract

Aujeszky's disease (AD), caused by Suid herpesvirus type 1 (SuHV-1), is an economically important disease in domestic swine. Thus, rigorous control programmes have been implemented and consecutively AD in domestic swine was successfully eradicated in many countries, including Austria. However, SuHV-1 continues to thrive in wild boar populations, as indicated by high seroprevalences in a number of European countries and by occasional cases of AD in hunting dogs. For the first time, SuHV-1 was detected in Austrian wild boar and a molecular characterization of SuHV-1 isolated from wild boar and hunting dogs was performed. Results of preliminary serological analyses suggest a regional SuHV-1 seroprevalence of over 30% in free-living and almost 70% in fenced wild boar from Eastern Austria. Molecular typing of Austrian SuHV-1 isolates of wild boar origin revealed the presence of two genetically distinct variants of SuHV-1, both capable of infecting dogs that have been exposed to infected wild boar during hunting.

摘要

奥耶斯基氏病(AD)由猪疱疹病毒 1 型(SuHV-1)引起,是家猪的一种重要经济疾病。因此,许多国家都实施了严格的控制计划,包括奥地利在内的一些国家已经成功根除了家猪中的 AD。然而,SuHV-1 继续在野猪种群中繁衍生息,这表明在许多欧洲国家的血清阳性率很高,并且在猎犬中偶尔会出现 AD 病例。SuHV-1 首次在奥地利野猪中被检测到,并对来自野猪和猎犬的 SuHV-1 分离株进行了分子特征描述。初步血清学分析的结果表明,在奥地利东部自由放养的野猪中,SuHV-1 的血清阳性率超过 30%,在围栏野猪中几乎为 70%。对来自野猪的奥地利 SuHV-1 分离株的分子分型显示,存在两种遗传上不同的 SuHV-1 变体,这两种变体都能够感染在狩猎期间接触感染野猪的猎犬。

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