Department of Pulmonary Diseases, Hopital Ambroise Pare, AP-HP, 9 avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France.
Clin Lung Cancer. 2012 Sep;13(5):363-8. doi: 10.1016/j.cllc.2011.11.010. Epub 2012 Jan 20.
The proportion of elderly patients with lung cancer is increasing. The objectives of this study were to describe the initial symptoms in elderly patients (≥ 70 years) with lung cancer and to describe the diagnostic and treatment delays.
We reviewed all consecutive patients with lung cancer that were diagnosed between 2006 and 2008 in our department. The initial symptoms and delays in the diagnosis and treatment in elderly patients were compared with those of younger patients.
One hundred ninety-three patients were included (26 small-cell cancers and 167 non-small-cell lung cancers [NSCLCs]). Ninety-two patients (47.7%) were ≥ 70 years old. No statistical differences were identified between the 2 groups concerning initial symptoms. In elderly patients, the delay between the initial symptoms and the first visit with a thoracic oncologist (median 1.6 months [IQR 23 days-3.3 months]), the delay between the first visit and the specific treatment (median 1.1 months [IQR 18 days-1.8 months]), and the delay between initial symptoms and the specific treatment (median 3 months [IQR 2-5.7 months]) were similar to those in the younger patients (P = .101, P = .084, and P = .671, respectively). Eighty-four percent of the elderly patients were actively treated vs. 98% of the younger patients (P = .001).
We identified no differences regarding the initial symptoms in elderly patients with lung cancer compared with those in younger patients. The delays in diagnosis and treatment were similar between the 2 groups.
老年肺癌患者的比例正在增加。本研究的目的是描述老年(≥70 岁)肺癌患者的首发症状,并描述诊断和治疗的延误情况。
我们回顾了 2006 年至 2008 年期间在我们科室诊断的所有连续肺癌患者。比较了老年患者与年轻患者的首发症状、诊断和治疗延误情况。
共纳入 193 例患者(26 例小细胞癌和 167 例非小细胞肺癌[NSCLC])。92 例(47.7%)患者年龄≥70 岁。两组患者的首发症状无统计学差异。在老年患者中,首发症状至首次就诊胸肿瘤科医生的时间(中位数 1.6 个月[IQR 23 天-3.3 个月])、首次就诊至特定治疗的时间(中位数 1.1 个月[IQR 18 天-1.8 个月])以及首发症状至特定治疗的时间(中位数 3 个月[IQR 2-5.7 个月])与年轻患者相似(P=0.101、P=0.084 和 P=0.671)。84%的老年患者接受了积极治疗,而年轻患者为 98%(P=0.001)。
与年轻患者相比,老年肺癌患者的首发症状无差异。两组患者的诊断和治疗延误情况相似。