Instituto Valenciano de Infertilidad, IVI-Lisboa, Lisbon, Portugal.
Fertil Steril. 2012 Mar;97(3):517-22. doi: 10.1016/j.fertnstert.2011.12.046. Epub 2012 Jan 21.
Vascular endothelial growth factor is the factor that causes increased capillary permeability and therefore the most serious manifestations of ovarian hyperstimulation syndrome. Dopamine agonists can both prevent and treat ovarian hyperstimulation syndrome by blocking expression of the vascular endothelial growth factor receptor.
血管内皮生长因子是导致毛细血管通透性增加的因素,也是卵巢过度刺激综合征最严重的表现。多巴胺激动剂通过阻断血管内皮生长因子受体的表达,既能预防又能治疗卵巢过度刺激综合征。