Department of Biological Engineering, Inha University, Incheon, South Korea.
J Chromatogr A. 2012 Mar 2;1227:67-72. doi: 10.1016/j.chroma.2011.12.030. Epub 2011 Dec 14.
Efficient recovery of ionic liquid (IL) from aqueous mixture of ILs and sugars (which derived from enzymatic or chemical catalyzed hydrolysis of ILs-pretreated biomass) is a major drawback for commercialization of biofuel and platform chemicals production from biomass utilized ILs as pretreatment solvent. In this study, simulated moving bed (SMB) chromatography equipped with ion exclusion column (containing [Emim]+ cation) was investigated to separate sugars (glucose and xylose) which are the main products from biomass hydrolysate and 1-ethyl-3-methylimidazolium acetate (EmimAc) which is the ILs used for biomass pretreatment. A four-zone SMB system with a configuration of 2-2-2-2 (2 ion exclusion columns in each zone) was used to recover glucose, xylose and EmimAc from their aqueous mixture with yield of 71.38, 99.37 and 98.92%, respectively. Moreover, the optimization of SMB zone configuration by simulation results in a complete recovery of ILs. This result indicates that for the first time, ion exclusion SMB chromatography could be used for complete recovery of ILs from aqueous sugar mixture.
从含离子液体 (IL) 和糖（由 IL 预处理的生物质经酶或化学催化水解而来）的水溶液混合物中高效回收 IL 是将生物燃料和平台化学品从用作预处理溶剂的 IL 生产商业化的主要障碍。在这项研究中，配备离子排斥柱（含有 [Emim]+阳离子）的模拟移动床 (SMB) 色谱法被用于分离糖（葡萄糖和木糖），它们是生物质水解产物中的主要产物，以及 1-乙基-3-甲基咪唑醋酸盐 (EmimAc)，这是用于生物质预处理的 IL。使用具有 2-2-2-2（每个区有 2 个离子排斥柱）配置的四区 SMB 系统，从其水溶液混合物中分别以 71.38%、99.37%和 98.92%的收率回收葡萄糖、木糖和 EmimAc。此外，通过模拟结果对 SMB 区配置进行优化，可实现 IL 的完全回收。这一结果表明，离子排斥 SMB 色谱法首次可用于从含糖的水溶液混合物中完全回收 IL。
